Table 2 Clinic pathological data and ATP synthase α-subunit expression in 168 breast cancers
From: ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer
α-ATP synthase expression | Total | P value | |||
|---|---|---|---|---|---|
Negative | Moderate | Strong | |||
Age | |||||
< 50 | 5 (7.0%) | 30 (42.3%) | 36 (50.7%) | 71(100%) | Not significant |
≥ 50 | 4 (4.1%) | 31 (32.0%) | 62 (63.9%) | 97 (100%) | |
Size | |||||
< 2 cm | 2 (13.3%) | 10 (66.7%) | 3 (20.0%) | 15 (100%) | P < 0.05 |
≥ 2 cm | 2 (3.6%) | 24 (42.8%) | 30 (53.6%) | 56 (100%) | |
Histological grade | |||||
Well differentiated | 3 (12.5%) | 11 (45.8%) | 10 (41.7%) | 24 (100%) | P < 0.05 |
Moderately differentiated | 6 (5.3%) | 43 (37.7%) | 65 (57.0%) | 114 (100%) | |
Poorly differentiated | 0 (0.0%) | 3 (15.0%) | 17 (85.0%) | 20 (100%) | |
TNM Stage | |||||
I | 2 (22.2%) | 4 (44.5%) | 3 (33.3%) | 9 (100%) | P < 0.05 |
II | 2 (4.6%) | 24 (54.5%) | 18 (40.9%) | 44 (100%) | |
III | 0 (0.0%) | 3 (23.1%) | 10 (76.9%) | 13 (100%) | |
Lymph node invasion | |||||
Positive | 3 (5.9%) | 18 (35.3%) | 30 (58.8%) | 51 (100%) | Not significant |
Negative | 2 (4.8%) | 11 (26.2%) | 29 (69.0%) | 42 (100%) | |