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Table 5 Representative amino acid sequences of monoclonal TCRBV families in CD8+ and CD8- cells (depleted CD8+ cells) from CHSB patients.

From: Molecular features of the complementarity determining region 3 motif of the T cell population and subsets in the blood of patients with chronic severe hepatitis B

Patientsa Vbeta CDR3 BJ Ratio
89 (CD8+) BV18 SAAYFCVSS RTGDTEA FFGQGTRLTVVED 1.1 11/11
133 (CD8+) BV11 SQYLCASS AGEL FFGEGSRLTVLED 2.2 11/20
115 (CD8+) BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 14/16
84 (CD8+) BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 27/27
119 (CD8-) BV11 SQYLCASS AGEL FFGEGSRLTVLED 2.2 14/22
89 (CD8-) BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 18/20
84 (CD8-) BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 17/20
89 (CD8+) BV5.2 SALYLCASS LTAGAYTGEL FFGEGSRLTVLED 2.2 11/29
  1. When the GMSP displayed a single peak (Figure 3), the cDNA of corresponding TCRBV family was re-amplified and PCR product was sequenced after cloning. The amino acid sequences of the max rate of TCRBV families are shown. a The cell subset for analysis in brackets.