Skip to main content

Table 4 Representative amino acid sequences of monoclonal TCRBV families in PBMCs from CSHB patients.

From: Molecular features of the complementarity determining region 3 motif of the T cell population and subsets in the blood of patients with chronic severe hepatitis B

Patients Vbeta CDR3 BJ Ratio
69 BV23 SALYFCASS VEGGNTI YFGEGSWLTVVED 1.3 21/21
90 BV22 SAMYFCASS DLGVAQ YFGPGTRLTVTED 2.7 9/20
75 BV22 SAMYFCASS DLGVAQ YFGPGTRLTVTED 2.7 4/18
90 BV18 SAAYFCASS RTGDTEA FFGQGTRLTVVED 1.1 21/21
75 BV18 SAAYFCASS RTGDTEA FFGQGTRLTVVED 1.1 21/21
105 BV18 SAAYFCASS RTGDTEA FFGQGTRLTVVED 1.1 21/21
107 BV11 SQYLCASS AGEL FFGEGSRLTVLED 2.2 5/21
131 BV11 SQYLCASS AGEL FFGEGSRLTVLED 2.2 9/20
138 BV11 SQYLCASS AGEL FFGEGSRLTVLE 2.2 9/18
172 BV11 SQYLCASS AGEL FFGEGSRLTVLED 2.2 3/21
172 BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 4/21
75 BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 7/8
83 BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 20/20
71 BV11 SQYLCATG VYNEQ FFGPGTRLTVLED 2.1 21/21
69 BV9 SAVYFCASS LQAGRGEQ FFGPGTRLTVLED 2.1 12/20
172 BV7 SALYLCASS QDSVTTGAQ YFGPGTRLLVLED 2.5 15/21
90 BV6 SAVYLCASS LAWEEQETQ YFGPGTRLLVLED 2.5 21/21
81 BV5.2 SALYLCASS LTAGAYTGEL FFGEGSRLTVLED 2.2 10/22
2 BV5.1 SALYLCASS LEWGASYEQ YFGPGTRLTVTED 2.7 9/20
  1. When the GMSP displayed a single peak (Figure 2), the cDNA of corresponding TCRBV family was re-amplified and PCR product was sequenced after cloning. The amino acid sequences of the max rate of TCRBV families are shown.