Representative GMSP with single-peak (monoclonal expansion) TCRBV in the CD8+ cell and CD8- cell from patients with CSHB. The TCRBV gene families shown on the top graphs correspond to P89CD8+ (BV18), P133CD8+ (BV11), P115CD8+ (BV11), and P84CD8+ (BV1); the TCRBVs shown in the bottom graphs correspond to P119CD8- (BV11), P89CD8- (BV11), P84CD8- (BV11), and P89CD8+ (BV5.2). The corresponding amino acid sequences are shown in Table 5. The melting temperature is on the x-axis of each plot. The negative first derivation of the decrease in fluorescence versus temperature (-dF/dT) is shown on the y-axis.