Representative GMSP with a single-peak (monoclonal expansion) of TCRBV in the PBMCs from patients with CSHB. The TCRBV gene families shown above in the top graphs correspond to P69 (BV23), P90 (BV22), P75 (BV22), P90 (BV18), P75 (BV18), and P105 (BV18); the TCRBVs shown on the bottom graphs correspond to P107 (BV11), P131 (BV11), P83 (BV11), P71 (BV11), P69 (BV9) and P172 (BV7). The corresponding amino acid sequences are shown in Table 4. The melting temperature is on the x-axis of each plot. The negative first derivation of the decrease in fluorescence versus temperature (-dF/dT) is shown on the y-axis.