Figure 4

Overall survival curves stratified by AEG-1 levels according to clinical stage, T and M classifications. (A, B) The differences of survival curves according to AEG-1 expression were seen in advanced clinical stage (B), but not in early clinical stage (A). (C, D) In the T3-T4 subgroup, patients with low AEG-1 expression showed significantly better overall survival (D). In the T1-T2 subgroup, the patients' overall survival times were not significantly different between the two groups (C). (E, F) Survival time was longer in patients with low AEG-1 expression regardless of distant metastasis (F). No significant difference between low and high AEG-1 expression groups were found in the M0 subgroup (E).