Figure 7From: Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes statusUsing the murine IAA ECL format, IA negative and IA positive individuals cannot be distinguished. Serum from 23 individuals (IA-, n = 14; IA+, n = 9) measured for IA by RBA were tested for IA using the murine IAA ECL format, but with an anti-human IgG ruthenium-labeled secondary. IA value is calculated as the average signal from triplicate wells divided by the background signal from triplicate wells with beads alone. NS = non-significant.Back to article page