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Figure 6 | Journal of Translational Medicine

Figure 6

From: Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status

Figure 6

IAA levels measured at 8-10 weeks of age can distinguish mice progressing to disease. Positive predictive IAA thresholds for each age were calculated as in Table 1 and are indicated by the dotted lines. IAA values measured at 7, 8-8.5, and 10 weeks of age are shown for each mouse that did (Db+) or did not (Db-) become diabetic by 20 weeks. IAA value is calculated as the average signal from triplicate wells divided by the background signal from triplicate wells with negative control sera.

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