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Table 1 Clinicopathological variables as predictors for disease-specific survival in 249 non-GIST STSs (univariate analyses, log-rank test).

From: The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

Characteristic Patients (n) Patients (%) Median survival (months) 5-Year survival (%) P
Age      
≤ 60 years 133 53 59 50 0.065
> 60 years 116 47 30 40  
Gender      
Male 110 44 41 46 0.390
Female 139 56 45 45  
Patient nationality      
Norwegian 167 67 63 51 0.011
Russian 82 33 22 34  
Histological entity      
Pleomorphic sarcoma 68 27 29 40 0.102
Leiomyosarcoma 67 27 45 46  
Liposarcoma 34 14 NR 67  
MF/MFT 20 8 43 50  
Angiosarcoma 13 5 10 31  
Rhabdomyosarcoma 16 6 17 38  
MPNST 11 5 49 45  
Synovial sarcoma 16 6 31 29  
Other STSs 4 2 NR 18  
Tumor localization      
Extremities 89 36 100 53 0.348
Trunk 47 29 32 44  
Retroperitoneum 37 25 25 38  
Head/Neck 18 7 15 41  
Visceral 58 23 30 42  
Tumor size      
≤ 5 cm 74 30 127 57 0.027
5-10 cm 91 37 44 45  
> 10 cm 81 32 28 36  
Missing 3 1    
Malignancy grade      
1 61 25 NR 74 <0.001
2 98 39 41 45  
3 90 36 16 26  
Tumor depth      
Superficial 17 7 NR 93 <0.001
Deep 232 93 36 42  
Metastasis at the time of diagnosis     
No 206 83 76 53 <0.001
Yes 43 17 10 10  
Surgery      
Yes 228 92 59 50 <0.001
No 21 8 5 0  
Resection margins      
Free 178 71 127 66 <0.001
Not free/no surgery 71 29 10 18  
Chemotherapy      
No 191 77 52 47 0.424
Yes 58 23 29 40  
Radiotherapy      
No 176 71 48 46 0.590
Yes 73 29 38 43  
  1. Abbreviations: non-GIST STS, non-gastro intestinal stromal tumor soft-tissue sarcoma; NR, not reached; MF/MFT, malignant fibroblastic/myofibroblastic tumors; MPNST, malignant peripheral nerve sheath tumor