Figure 2

Disease-specific survival curves for the investigated markers, their expression pattern and coexpression with steroid hormone receptors. A, p-Akt Thr³⁰⁸; B, Akt2; C, PI3K; D, p-Akt Thr³⁰⁸, by cellular expression pattern; E, p-Akt Ser⁴⁷³ in coexpression with ER, men; F, p-Akt Ser⁴⁷³ in coexpression with ER, women. Abbreviations: p-Akt Thr³⁰⁸, Akt phosphorylated at threonin 308; PI3K, phosphoinositide 3-kinase; p-Akt Ser⁴⁷³, Akt phosphorylated at serin 473; ER, estrogen receptor.