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Figure 4 | Journal of Translational Medicine

Figure 4

From: Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer

Figure 4

HLA-DR restriction analysis of STEAP 281-296 - and EZH2 95-109 -reactive CD4 T-cell clones. (A) L243 but not W6/32 inhibited IFN-γ production from HLA-DR restricted, STEAP281-296-reactive CD4 T-cell clones. (B) HLA-DR restriction analysis of EZH295-109-reactive CD4 T-cell clones. (C and D) STEAP281-296- and EZH295-109-reactive CD4 T-cell clones were tested for their capacity to recognize autologous PBMCs as APCs in the presence of various concentrations of peptide. Points means of triplicate determinations, bars SD. Points without bars had SD < 10% the value of the mean. Results are representative of two experiments that were done with the same samples.

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