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Figure 2 | Journal of Translational Medicine

Figure 2

From: Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma

Figure 2

Distribution of Tcregs and Tc17 cells in PBMCs and TILs from paired NPC patients. The proportion of Tcregs (A, B) and Tc17 cells (C, D) in total CD8+ T cells from PBMCs and freshly isolated TILs of paired NPC patients (n = 21) and healthy donors (HD, n = 21). Subsets were identified by intracellular staining of Foxp3 and IL-17 after PMA/ionomycin stimulation in vitro. Cumulative data show a significant increase in the number of Tcregs in PBMCs and TILs of NPC patients as compared with PBMCs of healthy donors and a significant decrease in Tc17 cells from PBMCs of NPC patients as compared with TILs from NPC patients and PBMCs from healthy donors.

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