Table 1 Patient's clinical and serological data
Normal values | Baseline | During treatment (*) | On remission | |
|---|---|---|---|---|
ESR | < 30 mm | 15 mm | 14 mm | 12 mm |
C reactive protein | < 0.5 mg/dl | 0.27 mg/dl | 0.15 mg/dl | 0.06 mg/dl |
IgG | 700 - 1600 mg/dl | 1390 mg/dl | 1290 mg/dl | 1295 mg/dl |
IgM | 20 - 230 mg/dl | 123 mg/dl | 142 mg/dl | 106 mg/dl |
Monoclonal component | negative | negative | negative | negative |
White cells count | 4500 - 10000/mm3 | 5310/mm3 | 2610/mm3 | 3280/mm3 |
Hemoglobin | 12 - 16 g/dl | 14.2 g/dl | 13.3 g/dl | 13.7 g/dl |
Platelets | 150000 - 350000/mm3 | 211000/mm3 | 178000/mm3 | 170000/mm3 |
Lactate dehydrogenase | 105 - 333 IU/L | 213 IU/L | 192 IU/L | 194 |
C4 levels | 10 - 40 mg/dl | 8 mg/dl | 12 mg/dl | 11 mg/dl |
C3 levels | 90 - 180 mg/dl | 81 mg/dl | 86 mg/dl | 89 mg/dl |
Antinuclear antibodies | negative | positive speckled 1: 160 | positive speckled 1: 160 | positive speckled 1: 160 |
Anti-Ro/SSA | negative | positive | positive | positive |
Anti-La/SSB | negative | negative | negative | negative |
Rheumatoid Factor | < 15 IU/L | 11 IU/L | 9 IU/L | 9 IU/L |
Cryoglobulinemia | negative | negative | negative | negative |
CD 4 | 36 - 50% | 40.1% | 43.2% | 44.2% |
CD 8 | 20 - 28% | 38.6% | 43.3% | 39.4% |
CD 3 | 65 - 77% | 80.1% | 89.3% | 82.7% |
CD 19 | 5 - 14% | 7.8% | 0.4% | 0.8% |
CD 16+56 | 3 - 15% | 10.2% | 7.7% | 7.9% |