A novel patient-derived intra-femoral xenograft model of bone metastatic prostate cancer that recapitulates mixed osteolytic and osteoblastic lesions

Table 2 PCSD1 tumor xenograft passaging and transplantation take-rate.

Tumor Passage No.	Number of mice injected	Number mice with tumor	Take-rate
P0
SC	10	10	100%
IF	8	8	100%
P1
SC	18	18	100%
IF	29	19	66%
P2
SC	10	10	100%
IF	23	14	67%

Tumor passage number: P0 = primagraft: primary patient sample injected; P1 = first serial passage of tumor cells, that is, tumor cells harvested from P0 tumors are re-implanted into new mice and tumors allowed to develop; P2 = second serial passage of xenograft tumors; SC = sub-cutaneously transplanted tumors; IF = intra-femorally transplanted tumors.

ISSN: 1479-5876