Skip to main content

Table 2 Univariate and multivariate analyses of prognostic factors for disease-free and overall survival of stage II and III colon carcinoma patients

From: High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis

 

DISEASE-FREE SURVIVAL

 

Univariate Analysis

Multivariate Analysis

Prognostic factors

HR 1 (95% CI) 2

p value

HR (95% CI)

p value

Stage III vs II

2.55 (1.41-4.60)

0.002

2.77 (1.45-5.28)

0.002

HCA2 relative score (+3/+2/-3/-2 vs others)

2.50 (0.18-5.31)

0.02

2.94 (1.36-6.34)

0.006

MEM-E/02 absolute score (0/1/2 vs 3)

1.90 (1.05-3.45)

0.03

1.82 (0.96-3.45)

0.06

T (3/4 vs 1/2)

1.26 (0.56-2.82)

0.58

  

Grading (2/3 vs 1)

1.95 (0.47-8.04)

0.36

  

HCA2 absolute score (0/1 vs 2/3)

1.47 (0.77-2.79)

0.25

  

HC10 absolute score (2/3 vs 0/1)

2.40 (0.74-7.74)

0.14

  

L31 absolute score (0/1 vs 2/3)

1.36 (0.73-2. 57)

0.33

  
 

OVERALL SURVIVAL

 

Univariate Analysis

Multivariate Analysis

Prognostic factors

HR 1 (95% CI) 2

p value

HR (95% CI)

p value

Stage III vs II

2.78 (1.45-5.34)

0.002

2.49 (1.23-5.04)

0.01

HCA2 relative score (+3/+2/-3/-2 vs others)

3.09 (1.43-6.69)

0.004

3.55 (1.61-7.87)

0.002

MEM-E/02 absolute score (0/1/2 vs 3)

1.96 (1.01-3.81)

0.05

1.81 (0.90-3.63)

0.09

T (3/4 vs 1/2)

1.41 (0.55-3.61)

0.48

  

Grading (2/3 vs 1)

1.57 (0.38-6.52)

0.54

  

HCA2 absolute score (0/1 vs 2/3)

1.66 (0.83-3.31)

0.15

  

HC10 absolute score (2/3 vs 0/1)

1.91 (0.59-6.22)

0.28

  

L31 absolute score (0/1 vs 2/3)

1.21 (0.60-2.44)

0.61

  
  1. 1 HR: hazard risk
  2. 2 CI: 95% confidence interval
  3. Significant correlations boldface