Skip to main content
Figure 6 | Journal of Translational Medicine

Figure 6

From: Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: Is that a latent disadvantage?

Figure 6

Co-localization of iNOS and insulin in islets, fenofibrate upregulated iNOS expression in the islet beta cells. Representative confocal microscopy images showed the co-localization of iNOS and insulin in islets. Paraffin-embedded pancreas sections were double immunostained by anti-insulin antibody and TRITC secondary (red) and anti-iNOS antibody and FITC secondary (green). A-C: insulin immunoreactivity; D-F: iNOS immunoreactivity; G-I: co-localization of insulin-iNOS indicated by yellowish fluorescence. Scale bar: 30 μm. Nor, normal rats. Con, water treated obese MSG rats. Fen, fenofibrate treated obese MSG rats.

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us