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Figure 10 | Journal of Translational Medicine

Figure 10

From: Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone

Figure 10

ROS generation and NADPH oxidase activity by PTEC. (A) Up-regulation of ROS generation and (B) NADPH oxidase activity by PTEC cultured with Aldo (10-10 M), AngII (10-10 M) or 4 fold diluted IgA-HMC medium prepared from IgAN patients (IgAN); Similar up-regulation was not observed with IgA-HMC medium from controls (Ctl) or pIgA alone (IgA). ** signify p < 0.01 when compared with data from PTEC cultured in plain medium. The results represent the mean ± SD from five individual experiments.

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