Figure 1From: Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosteroneIncreased expression of CYP11B2 in HMC cultured with pIgA. (A) There was increased expression of CYP11B2 mRNA and (B) CYP11B2 protein, but not 11β-HSD2, by HMC cultured with pIgA from patients (IgAN, n = 27) as compared to that of the controls (Control, n = 22). The results represent the mean ± SD. (C) Increased expression of CYP11B2 (arrow) in HMC was confirmed by immunofluorescence staining (magnification × 200).Back to article page