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Table 1 Patients' age, gender, tumor staging, frequencies of EGFR-specific T cells a and EGFR score b

From: EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma

No Age (yrs) TNM EGFR score KLF (%) YLN (%)
1 76 T4 N0 M0 1 0.0029 0.0027
2 84 T3 N1 MX 2 0.0125 0.0084
3 59 T4 N0 MX 2 0.0034 0.0074
4 61 T1 N0 MX 4 0.0050 0.0143
5 55 T2 N0 MX 4 0.0145 0.0193
6 56 T3 N2b M0 4 0.0216 0.0164
7 83 T2 N0 MX 4 0.0107 0.0241
8 67 T1 N0 M0 4 0.0069 0.0061
9 41 T2 N2a MX 4 0.0089 0.0045
10 68 T3 N2 M0 6 0.0062 0.0045
11 55 T2 N2 MX 6 0.0134 0.0145
  64.1   3.7 0.015 ± 0.001 0.014 ± 0.002
12 58 T3 N1 M0 9 0.0265 0.0758
13 52 T4 N2b M0 9 0.0351 0.0387
14 64 T3 N1 M0 12 0.0218 0.0097
15 60 T3 N0 MX 12 0.0409 0.0549
16 62 T2 N2a MX 12 0.0234 0.0748
  59.2   10.8 0.029 ± 0.008 0.051 ± 0.028
  1. a - The frequency of EGFR-specific T cells in PBMC are shown for KLF (pentamer) and YLN (tetramer) peptides in percent (%) of CD8 positive T cells in HNSCC patients with low EGFR score (2-6) and high EGFR score (9-12). All mean values are printed in bold for each patient group.
  2. b - EGFR scores were calculated as staining intensity (1-4) multiplied by the number of EGFR-positive cells (0-4) determined by immunohistochemistry.