Table 2 Univariate and multivariate analyses of PFS
Univariate Analysis | |||
|---|---|---|---|
N | HR (95% CI) | p | |
Age (years) | 60 | 1.01 (0.98-1.04) | 0.63 |
PS 0 | 14 | 1.03 (0.52-2.04) | 0.94 |
PS 1-2 | 46 | 1 Ref. | |
Male | 36 | 1.48 (0.81-2.70) | 0.21 |
Female | 24 | 1 Ref. | |
Adenocarcinoma | 39 | 1 Ref. | 0.05 |
Non-adenocarcinoma | 21 | 1.84 (1.01-3.33) | |
Smoker | 22 | 1.26 (0.64-2.49) | 0.51 |
Non- smoker | 27 | 1 Ref. | |
EGFR mutated | 9 | 1 Ref. | 0.32 |
EGFR wild-type | 41 | 1.55 (0.65-3.73) | |
K-ras mutated | 10 | 1.21 (0.58-2.53) | 0.62 |
K-ras wild-type | 46 | 1 Ref. | |
Low BRCA1&AEG1 expression | 18 | 1 Ref. | |
High BRCA1&AEG1 expression | 17 | 3.08 (1.33-7.15) | 0.009 |
Other combinations of BRCA1&AEG1 expression | 25 | 1.70 (0.82-3.53) | 0.15 |
Multivariate Analysis | |||
Low BRCA1&AEG1 expression | 18 | 1 Ref. | |
High BRCA1&AEG1 expression | 17 | 3.11 (1.30-7.47) | 0.01 |
Other combinations of BRCA1&AEG1 expression | 25 | 2.18 (0.99-4.78) | 0.05 |
Adenocarcinoma | 39 | 1 Ref. | |
Non-adenocarcinoma | 21 | 1.52 (0.79-2.91) | 0.21 |
Male | 36 | 1.60 (0.84-3.07) | 0.16 |
Female | 24 | 1 Ref. | |