Table 2 Univariate proportional hazards models of risk of biochemical recurrence after prostatectomy associated with established prognostic factors and individual CTAs*

Age (years)

1.04 (0.999, 1.09)

0.054

PSA (ng/ml)

1.04 (1.004, 1.07)

0.028

Prostatectomy stage

   Organ confined

1.0

ref

   Extraprostatic extension

4.53 (1.05, 19.47)

0.042

   Seminal vesicle involvement

7.49 (1.60, 35.10)

0.011

   Lymph node metastases

10.81 (2.37, 49.23)

0.002

Prostatectomy Gleason score

   ≤ 6

1.0

ref

   7 (3 + 4)

26.83 (3.48, 206.73)

0.002

   7 (4 + 3)

39.01 (4.65, 327.17)

0.0007

   8 to 10

35.01 (4.64, 264.19)

0.0006

CTAs

   CEP55

3.59 (1.50-8.60)

0.004

   NUF2

2.28 (1.11-4.67)

0.024

   PAGE4

0.44 (0.21-0.93)

0.031

   PBK

1.78 (0.92-3.43)

0.085

   TTK

1.55 (0.82-2.94)

0.179