Figure 2

Cytokine secretion assessed by signal-3 assay. CD40L-transfected mouse fibroblasts were used as stimulators for DCs mimicking T cell contact. Supernatants were collected after 24 h of coculture. Cytokines were measured by standard ELISA. Independent experiments were performed with a number of n = 4-12 donors for C, CP, R, and RP in HCs and AML patients.