Figure 5

Protein expression levels of apoptosis-related in infarct area. A) Caspase 3 protein expression was notably higher in group 2 than in other groups, notably higher in group 3 and 4, but no significant difference between group 3 and 4 and between group 1 and 5. † vs. other groups, p < 0.0001 (ANOVA test). B) Significantly higher mitochondrial protein expression of Bax in group 2 than in other groups. Significant elevation also noted in group 3 and 4 compared with that in group 1 and 5, and notably higher in group 5 than in group 1, but no remarkable difference between group 3 and 4. † vs. other groups, p < 0.001 (ANOVA test). C) Cytosolic protein expression of Bax substantially lower in group 2 than in other groups, but no difference between group 1 and 5 or among group 3, 4, and 5. † vs. other groups, p < 0.001 (ANOVA test). D) Bcl-2 protein expression notably lower in group 2 than in other groups, significantly lower in group 3 and 4 than in group 1 and 5, but no significant difference between group 1 and 5 or between group 3 and 4. † vs. other groups, p < 0.001 (ANOVA test). Symbols (*, †, ‡, §) in A) to D) indicate significance (at 0.05 level) (by Scheffe multiple-comparison post hoc test).