Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals - the Swiss HIV Cohort Study

Table 1 Exclusion criteria for comparison of GRT versus GRT + rPRT

	All N (%)	GRT N (%)	GRT + rPRT N (%)
Ineligible tests - n (% of total tests)	1459	1120	339
No change of ART after RT	708 (49.0)	532 (47.5)	176 (51.9)
Change of ART only >1 year after last RT	526 (36.1)	411 (36.7)	116 (34.2)
Off treatment for >6 months after RT	126 (8.6)	105(9.4)	21 (6.2)
No RNA during study period*	98 (6.7)	74 (6.6)	25 (7.4)
Other#	1 (0.01)	0.0	1 (0.3)

* The study period is the time from the 1^st change of ART after RT until the earliest of either changing ART due to failure (RNA >400), going off treatment, or December 31, 2008.
# Participation in a structured treatment interruption trial.
RT = resistance test, GRT = genotype RT, rPRT = replicative phenotype RT, cART = combined antiretroviral therapy

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