Figure 5

Immunohistochemical staining against hBD-3 (400-fold magnification). A:. BONJ. Immunoreactivity could be detected along the endosteal cell lines (stars). Inside bone trabecula (BT) numerous positive cell reactions of osteocytes are visible (arrows), which indicate expression of hBD-3. BM, bone marrow area. B: ORN. Strong positivity in osteoblasts could be detected along the endosteal cell line (arrows). Inside mineralized bone trabecula (BT) only weak positivity in osteocytes is evident. C: Healthy bone controls. Positive staining could be detected along the endosteal cell lines (arrows) with moderate positivity of osteoblasts, which indicates the presence of hBD-3. Inside bone trabecula (BT) a no positive osteocytes are visible.