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Figure 4 | Journal of Translational Medicine

Figure 4

From: Increased human defensine levels hint at an inflammatory etiology of bisphosphonate-associated osteonecrosis of the jaw: An immunohistological study

Figure 4

Immunohistochemical staining against hBD-2 (400-fold magnification). A: BONJ. Smooth positive staining could be detected along the endosteal cell lines. Inside bone trabecula (BT) scattered positive cell reactions of osteocytes are visible, which indicate expression of hBD-2. B: ORN. Negative empty osteocytes lacunae (arrow) and enhanced positivity in the endosteal cell line (star) are evident. C: Healthy bone samples. Partial positivity of osteocytes (arrow) and weak cytoplasmic positivity of stromal cells (stars) within the bone marrow area (BM) are visible.

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