Figure 3

Immunoreactivity against hBD-2 and -3 was significantly higher in bisphosphonate-associated osteonecrosis of the jaw than in infected osteoradionecrosis and healthy jaw bone samples. Value distribution of hBD-1 trough 3 expression in bone shown as boxplots divided into groups. The labeling index was defined as the ratio of stained osteocytes vs. total number of osteocytes and osteocyte lacunae inside the ROI. Outliers are marked as circles.