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Table 3 IC50 values of RCC cell lines treated with NVP-BEZ235

From: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

Cell Line

IC50 NVP-BEZ235 (ηM)

A498

25

ACHN

30

Caki-1

26

Caki-2

164

769-P

67

786-0

87

  1. In all 6 RCC cell lines the IC50s of NVP-BEZ235 were in the ηM range.