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Figure 2 | Journal of Translational Medicine

Figure 2

From: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer

Figure 2

Associations between marker expression and clinical/pathological variables. (A) Associations between target expression (p85, p110α and mTOR) and histologic subtype. Expression of all three targets was higher in sarcomatoid tumors. (B) Associations between target expression and tumor stage and Fuhrman grade. p85 and mTOR were associated with high grade and p85 with high stage. p110α levels were not associated with stage or grade. (C) Kaplan-Meier survival curves of quartiles of AQUA scores for the three targets. High levels of both p85 and mTOR were associated with decreased survival.

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