Table 2 Oxygen consumption by mitochondria from the three experimental groups, using succinate as substrate.
From: Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats
Young controls (yCO) (n = 6) | Untreated old rats (O) (n = 6) | Old rats treated with IGF-II O+IGF-II (n = 6) | |
|---|---|---|---|
State 4 (nAgO·mg-1·min-1) | 27.55 ± 2.85 | 19.95 ± 1.90 | 23.00 ± 2.00 |
State 3 (nAgO·mg-1·min-1) | 88.35 ± 6.65 | 62.70 ± 5.70a | 74.00 ± 15.00 |
RCR | 3.30 ± 0.80 | 3.10 ± 0.50 | 3.20 ± 0.90 |
ADP/Oxygen | 1.71 ± 0.19 | 1.05 ± 0.28a | 2.01 ± 0.41b |