Skip to main content

Table 1 Mitochondrial Membrane Potential (expressed as arbitrary units of fluorescence, AUF) in isolated liver mitochondria from the three experimental groups, using succinate as substrate.

From: Liver mitochondrial dysfunction is reverted by insulin-like growth factor II (IGF-II) in aging rats

 

Young controls (yCO) (n = 6)

Untreated old rats (O)

(n = 6)

Old rats treated with IGF-II O+IGF-II (n = 6)

Succinate (State 4)

191.90 ± 18.05

160.55 ± 16.15a

188.60 ± 19.00b

   + ADP (State 3)

133.95 ± 13.30

125.40 ± 17.10

131.40 ± 11.40

   + Oligomycin

217.55 ± 17.10

158.65 ± 17.10a

223.85 ± 14.25b

  1. Values are mean ± SEM. P, ns yCO group vs. O+IGF-II group in all conditions.
  2. a P < 0.05 vs yCO
  3. b P < 0.05 vs O