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Table 5 Univariate and multivariate linear regression analysis between various clinicopathological variables and RIN for 186 prostate samples1.

From: Biobanking after robotic-assisted radical prostatectomy: a quality assessment of providing prostate tissue for RNA studies

  Univariate Multivariate2
Variable B SE CI (95%) p-value B SE CI (95%) p-value
Constant - - - - 6.395 0.531 5.347/7.444 < 0.001
Benign/malignant3 1.724 0.261 1.209/2.238 < 0.001 0.867 0.261 0.352/1.382 0.001
Stromal/epithelial4 2.336 0.278 1.789/2.884 < 0.001 1.738 0.292 1.161/2.316 < 0.001
Age -0.011 0.021 -0.054/0.031 0.600 - - - -
Body Mass Index -0.048 0.042 -0.131/0.035 0.256 - - - -
Preoperative PSA -0.015 0.039 -0.091/0.062 0.709 - - - -
Prostate volume -1.181 0.306 -1.784/-0.577 < 0.001 -0.690 0.262 -1.207/-0.173 0.009
Gleason sum 0.093 0.409 -0.715/0.900 0.821 - - - -
% cancer 0.002 0.021 -0.040/0.043 0.939 - - - -
Pathological stage 0.254 0.336 -0.410/0.917 0.451 - - - -
Positive surgical margin 0.645 0.446 -0.234/1.525 0.150 - - - -
Estimated blood loss -0.002 0.005 -0.011/0.008 0.735 - - - -
Intraoperative time -0.017 0.011 -0.039/0.005 0.136 - - - -
Collection time -0.001 0.12 -0.024/0.023 0.956 - - - -
Processing time -0.012 0.012 -0.036/0.012 0.313 - - - -
Total WIT -0.010 0.007 -0.022/0.003 0.147 - - - -
Total operating time -0.012 0.004 -0.019/-0.004 0.003 -0.006 0.003 -0.012/0.000 0.050
Storage time 0.067 0.067 -0.066/0.200 0.323 - - - -
  1. 1All 186 samples were included in the regression analysis with the n number of each variable corresponding to those in Tables 1 and 3; 2Multivariate linear analysis using the best model; 3Benign (0), malignant (1); 4stromal (0), epithelial (1).
  2. Abbreviations: B, unstandardised correlation coefficient; CI, 95% confidence interval; SE, standard error; WIT, warm ischaemia time.