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Figure 8 | Journal of Translational Medicine

Figure 8

From: Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model

Figure 8

Proposed mechanisms underlying the improvement in pulmonary functions after adipose-derived mesenchymal stem cell (ADMSC) treatment in a rodent model of pulmonary ischemia-reperfusion (IR) injury. vWF :von Willebrand factor, ET-1: Endothelin-1; TNF-α: Tumor necrosis factor-α; MMP-9: Matrix metalloproteinase-9; NF-κB: Nuclear factor kappa B; Cx43: Connexin43; IL-10: Interleukin-10; eNOS: Endothelial nitric oxide synthase; ICAM-1: Intercellular Adhesion Molecule-1; VCAM-1: Vascular cell adhesion molecule; HO-1: Heme oxygenase-1; NQO1: NAD(P)H quinone oxidoreductase; GR: Glutathione reductase; GPx: Glutathione peroxidase; Cyt C: Cytochrome C; RVSBP: Right ventricular systolic blood pressure; Sat O2: Oxygen saturation.

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