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Figure 6 | Journal of Translational Medicine

Figure 6

From: Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model

Figure 6

Adipose-Derived Mesenchymal Stem Cell (ADMSC) Treatment Inhibited Inflammation and Reactive Oxygen Species Generation in Lung Parenchyma after Ischemia-Reperfusion (IR) Injury. Notably higher protein expressions of TNF-α (A) and NF-κB (B) in IR group than in normal control and IR + ADMSC groups, but lack of difference between normal control and IR + ADMSC groups. *all p values < 0.04 between the indicated groups. Western blotting (C) showing notable increase in the oxidative index, protein carbonyls, in IR group compared with control group and IR + ADMSC group, and notably higher in IR + ADMSC group than in control group. *p < 0.05 between the indicated groups. Remarkably higher protein expressions of HO-1 (D) and NQO-1 (E) in IR and IR + ADMSC groups than in control group, and markedly higher in IR + ADMSC group than in IR group. *all p values < 0.04 between the indicated groups. n = 6 for each group. Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test).

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