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Figure 5 | Journal of Translational Medicine

Figure 5

From: Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model

Figure 5

Adipose-Derived Mesenchymal Stem Cell (ADMSC) Treatment Inhibited Inflammation in Lung Parenchyma after IR Injury. (Upper Panel) Immunofluorescent (IF) staining (200 x) of CD68+ cells (n = 6). Note the notably higher number of CD68+ cells (yellow arrows) in ischemia-reperfusion (IR) group (B) than in normal-control (A) and IR + ADMSC (C) groups. D) *p < 0.001 between the indicated groups. Scale bars in right lower corner represent 50 μm. (Lower Panel) Western blot analyses showing significantly higher protein expressions of intercellular adhesion molecule (ICAM)-1 (E) and vascular adhesion molecule (VCAM)-1 (F) in IR group than in other groups. E) *p < 0.03 between the indicated groups. F) *p < 0.05 between the indicated groups. Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test).

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