Impact of Adipose-Derived Mesenchymal Stem Cells (ADMSC) Transplantation on the Severity of IR-Induced Lung Parenchymal Injury. Number of alveolar sacs and crowded area (was defined in methodology section) under microscope (100×) at 72 h following ischemia-reperfusion (IR) procedure (n = 6). Notably reduced number of alveolar sacs in IR group (B) compared with IR + ADMSC (C) and normal control (A) groups (H & E). Also note more compact lung parenchyma with thickened septum in IR group than in other groups. Septal thickening more prominent in some alveoli in IR group than in IR + ADMSC and normal control groups. Scale bars in right lower corner represent 100 μm. D) *p < 0.001 between the indicated groups. E) *p < 0.0001 between the indicated groups. Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test).