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Figure 1 | Journal of Translational Medicine

Figure 1

From: Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration

Figure 1

C5a promotes the expression of IL-22 and IL-17 from T cells. (A) IL-22 and IL-17 in 3-day culture supernatants of PBMCs from 14 AMD patients and 14 controls. (B) C5a induced IL-22/IL-17 expression in both controls and AMD patients were subgrouped based on CFH genotypes. (C) Intracytoplasmic staining of IL-22 and IL-17 from both controls and AMD patients after 5 days of culture with or without C5a and C5aR antagonist.

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