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Table 1 Echocardiographic Findings Prior to and on Day 90 after AMI

From: Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction

Variables

Group I (n = 6)

Group II (n = 6)

Group III (n = 6)

Group IV (n = 6)

Group V (n = 6)

Group VI (n = 6)

P‡ value

LVEF (%)*

81.5 ± 2.07

80.8 ± 1.39

79.7 ± 1.48

80.8 ± 1.44

81.7 ± 3.18

80.2 ± 1.75

0.512

FS (%)*

42.4 ± 1.95

43.7 ± 2.46

42.9 ± 1.26

43.2 ± 1.82

44.2 ± 1.88

43.6 ± 1.61

0.648

LVEDD (cm)*

0.60 ± 0.01

0.61 ± 0.01

0.62 ± 0.02

0.60 ± 0.02

0.59 ± 0.03

0.60 ± 0.01

0.871

LVESD (cm)*

0.33 ± 0.02

0.32 ± 0.01

0.34 ± 0.01

0.32 ± 0.02

0.31 ± 0.03

0.33 ± 0.01

0.794

LVEF (%)†

79.8a ± 1.46

79.3a ± 2.44

79.2a ± 2.07

63.4b ± 1.71

69.8c ± 2.03

74.8d ± 2.87

<0.0001

FS (%)†

43.0a ± 1.21

43.2a ± 1.75

43.1a ± 0.85

30.9b ± 0.50

35.2c ± 2.19

38.7d ± 1.21

<0.0001

LVEDD (cm)†

0.61 ± 0.01a

0.60 ± 0.01a

0.59 ± 0.02a

1.0 ± 0.01b

0.77 ± 0.02c

0.69 ± 0.03d

<0.0001

LVESD (cm)†

0.34 ± 0.01a

0.31 ± 0.02a

0.33 ± 0.02a

0.66 ± 0.02b

0.49 ± 0.02c

0.40 ± 0.02d

<0.0001

  1. Data expressed as means ± SD.
  2. AMI = acute myocardial infarction; LVEF = left ventricular ejection fraction; FS = fractional shortening; LVEDD = left ventricular end-diastolic dimension; LVESD = left ventricular systolic dimension.
  3. * Transthoracic echocardiography performed at day 0 prior to AMI induction.
  4. † Transthoracic echocardiography performed on day 90 after AMI induction.
  5. Group I = sham control treated by fresh medium;
  6. Group II = sham control treated by normal heart myocardium-derived conditioned medium (MDCM);
  7. Group III = sham control treated by infarcted-related MDCM;
  8. Group IV = AMI induction treated by fresh medium;
  9. Group V = AMI induction treated by normal heart MDCM;
  10. Group VI = AMI induction treated by infarcted-related MDCM.
  11. ‡ One-way ANOVA on the arcsine transformed data was used to improve the normality for statistical analysis. Letters (a, b, c, d) indicate significance (at 0.05 level) by Bonferroni multiple comparison post hoc test (a versus b, c, d, b versus c, d, c versus d, all p values <0.05)