Figure 4

Gelatinolytic activity of MMP-2 and MMP-9 in supernatant of cultured neonatal cardiac fibroblasts. Expressions of supernatant gelatinolytic activity of MMP-2 and MMP-9 in fresh medium versus different conditioned media (n = 6 in each group). (Left Panel) Pro-MMP-2 and MMP-2 (cleaved). (1) G1 vs. 10% G2 vs. 10% G3, p < 0.0001 (* vs. ‡ or † vs. ¶, p < 0.001). (2) G1 vs. 20% G2 vs. 20% G3, p < 0.0001 (§ vs. ** or # vs. ##, p < 0.001). (Right Panel) Pro-MMP-9 and MMP-9 (cleaved). (1) G1 vs. 10% G2 vs. 10% G3, p < 0.0001 (* vs. ‡ or † vs. ¶, p < 0.001). (2) G1 vs. 20% G2 vs. 20% G3, p < 0.0001 (§ vs. ** or # vs. ##, p < 0.001).