Table 2 Range of threshold values at maximal likelihood ratio and associated sensitivity and specificity values for each protease tested
Range | Enzyme | Index | Sensitivity | Specificity |
|---|---|---|---|---|
.03-0.11 ng | Cathepsin K | 72% | 100% | 100% |
40-55 ng | Cathepsin L | 27% | 100% | 80% |
4639-5009 AU | MMP-9 | 7% | 80% | 90% |
6447-7063 AU | proMMP-9 | 9% | 70% | 90% |
5334-5872 AU | MMP-2 | 9% | 60% | 90% |
4762-5541 AU | proMMP-2 | 14% | 80% | 80% |