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Table 3 Antioxidant enzymes activities in brain and liver

From: Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats

   Young controls (yCO) (n = 8) Untreated old rats (O) (n = 8) Old rats treated with IGF-II (O+IGF-II) (n = 8)
In cortex Catalase (U/mg prot) 22.8 ± 0.85 18.90 ± 1.05a 20.2 ± 1.2b
  SOD (U/mg prot) 3.99 ± 0.09 5.32 ± 0.38a 4.8 ± 0.2
  GPX (mU/mg prot) 89.3 ± 2.85 77.9 ± 2.85a 108 ± 5b
  GRD (U/mg prot) 41.80 ± 0.09 42.75 ± 1.9 46 ± 2
In hippocampus Catalase (U/mg prot) 9.40 ± 0.47 15.01 ± 2.09a 7.9 ± 1.1c
  SOD (U/mg prot) 1.23 ± 0.09 1.99 ± 0.19d 1.3 ± 0.2c
  GPX (mU/mg prot) 55.1 ± 2.85 83.6 ± 4.75d 66 ± 5
  GRD (U/mg prot) 31.35 ± 0.09 42.75 ± 2.85a 35 ± 4
In liver Catalase (KU/mg) 2.85 ± 0.28 1.90 ± 0.19b 2.70 ± 0.60
  SOD (U/mg) 11.59 ± 1.71 12.25 ± 1.99 18.20 ± 2.00
  GPX (U/mg) 1.04 ± 0.09 2.09 ± 0.19b 2.10 ± 0.10b
  1. Values are expressed as ± SEM. prot, Protein.
  2. a P < 0.01 vs yCO
  3. b P < 0.05 vs yCO
  4. c P < 0.05 vs O
  5. d P < 0.001 vs yCO