Table 3 Antioxidant enzymes activities in brain and liver
From: Hepatoprotection and neuroprotection induced by low doses of IGF-II in aging rats
Young controls (yCO) (n = 8) | Untreated old rats (O) (n = 8) | Old rats treated with IGF-II (O+IGF-II) (n = 8) | ||
|---|---|---|---|---|
In cortex | Catalase (U/mg prot) | 22.8 ± 0.85 | 18.90 ± 1.05a | 20.2 ± 1.2b |
SOD (U/mg prot) | 3.99 ± 0.09 | 5.32 ± 0.38a | 4.8 ± 0.2 | |
GPX (mU/mg prot) | 89.3 ± 2.85 | 77.9 ± 2.85a | 108 ± 5b | |
GRD (U/mg prot) | 41.80 ± 0.09 | 42.75 ± 1.9 | 46 ± 2 | |
In hippocampus | Catalase (U/mg prot) | 9.40 ± 0.47 | 15.01 ± 2.09a | 7.9 ± 1.1c |
SOD (U/mg prot) | 1.23 ± 0.09 | 1.99 ± 0.19d | 1.3 ± 0.2c | |
GPX (mU/mg prot) | 55.1 ± 2.85 | 83.6 ± 4.75d | 66 ± 5 | |
GRD (U/mg prot) | 31.35 ± 0.09 | 42.75 ± 2.85a | 35 ± 4 | |
In liver | Catalase (KU/mg) | 2.85 ± 0.28 | 1.90 ± 0.19b | 2.70 ± 0.60 |
SOD (U/mg) | 11.59 ± 1.71 | 12.25 ± 1.99 | 18.20 ± 2.00 | |
GPX (U/mg) | 1.04 ± 0.09 | 2.09 ± 0.19b | 2.10 ± 0.10b |