Figure 4

Spectratyping profile of B cell-reconstituted NOD.Igμ^null mice following cyclophosphamide treatment. Spectratype analysis of BV-BC expansions for pancreas-infiltrating T cells at 10 weeks post-B cell reconstitution of NOD.Igμ^null mice are shown, following treatment with cyclophosphamide (black bars) in comparison to 10 weeks old age-matched of NOD.Igμ^null mice reconstituted with B cells (white bars), and diabetic NOD.Igμ^null mice reconstituted with B cells (grey bars).