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Table 1 Clinical and pathological characterization of IBC versus non-IBC patients

From: Cathepsin B: a potential prognostic marker for inflammatory breast cancer

Clinical characteristic

IBC

n= 23 (%)

Non-IBC

n= 27 (%)

p-value

Age

   

Range

29-60

33-67

0.001a*

Mean ± SD

40.9 ± 7.5

49.9 ± 9.1

t- test

Tumor size‡

   

Mean ± SD

6.5 ± 3.3

4.31 ± 2.30

1.000b

< 2

1 (5.6%)

1 (3.7%)

 

≥ 2

17 (94.4%)

26 (96.3%)

 

Tumor grade

   

I- II

15 (65%)

21 (77.8%)

0.511b

III

8(35%)

6 (22.2%)

 

Axillary Lymph Node Status†

   

Negative

0(0%)

7 (25.9%)

0.037b*

< 4

3 (15%)

9 (33.4%)

 

4-7

6 (30%)

6 (22.2%)

 

≥ 8

11(55%)

5 (18.5%)

 

ER

   

Positive

6 (27.3%)

6 (22.2%)

 

Negative

17 (72.7%)

21 (77.8%)

0.747b

PR

   

Positive

7 (31.8%)

8 (29.6%)

1.000b

Negative

16 (68.2%)

19 (70.4%)

 

HER-2

   

Positive

4 (18.2%)

4 (14.8%)

1.000b

Negative

19 (81.8%)

23 (85.2%)

 

Lymphovascular invasion

   

Positive

17 (73.9%)

3 (11.1%)

0.000b*

Negative

6 (26.1%)

24 (88.9%)

 

Tumor emboli

   

Positive

23 (100%)

3 (11.1%)

0.000b*

Negative

0

24 (88.9%)

 
  1. * Significant p value calculated by aStudent- T test or bFisher's exactTest
  2. ‡ n = 18 (five IBC patients did not have a tumor mass)
  3. † n = 20 (three patients were not evaluated because they died before surgery)