Table 1 Clinical Characteristics Based on Autoantibody Status
From: Rapid induction of autoantibodies during ARDS and septic shock
| Â | Autoantibody Positivea(n = 20) | Autoantibody Negativea(n = 15) |
|---|---|---|
ARDS | Â | Â |
Age yrs (mean ± SD) | 45 ± 14 | 52 ± 16 |
Gender | 8 male (40%) | 10 male (67%) |
APACHE 3 score (mean ± SD) | 58 ± 17 | 62 ± 16 |
Methylprednisolone treatmentb | 13/20 (65%) | 9/15 (60%) |
Infections | Gram positive bacteria: 12 Gram negative bacteria: 3 Fungal: 1 Culture negative: 5 | Gram positive bacteria: 4 Gram negative Bacteria: 7 Fungal: 1 Viral: 1 Culture negative: 2 |
In-hospital survival | 18/20 (90%) | 9/15 (60%) |
Severe Sepsis | Â | Â |
| Â | Autoantibody Positive a (n = 6) | Autoantibody Negative a (n = 7) |
Age yrs (mean ± SD) | 54 ± 21 | 63 ± 18 |
Gender | 5 male (83%) | 7 male (100%) |
APACHE 3 score (mean ± SD) | 75 ± 26 | 68 ± 23 |
Hydrocortisone treatmentc | 5/6 (83%) | 5/7 (71%) |
Infections | Gram positive bacteria: 6 Gram negative bacteria: 0 | Gram positive bacteria: 3 Gram negative bacteria: 4 |
In-hospital survival | 4/6 (67%) | 5/7 (71%) |