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Table 2 Results of OSNA and histology (H&E Staining and CK19 IHC) for 184 LN

From: One Step Nucleic Acid Amplification (OSNA) - a new method for lymph node staging in colorectal carcinomas

OSNA

HISTOLOGIC INVESTIGATION

 

Macrometastases

Micrometastases

Negative

++

27

2

2 (1)

+

8

-

3 (2)

-

3 (2)

-

139

Total

38 (37)

2

144 (142)

  1. Numbers in brackets indicate samples after discordant sample analysis, ++: CK19 mRNA copies/μL higher than 5000, +:CK19 mRNA between 250 - 5000 copies/μL, -: CK 19 mRNA copies/μL less than 250