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Table 2 The sensitivity of CDC25B-Abs, CEA, CYFRA21-1 and SCC-Ag in detection ESCC.

From: Anti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma

Tumor Markers

Total

n

Positive

Negative

 
  

n (%)

n (%)

P

CDC25B-Abs

134

76 (56.7)

58 (43.3)

 

SCC-Ag

134

23 (17.2)

111 (82.8)

 

CEA

134

18 (13.4)

116 (86.6)

 

CYFRA 21-1

134

43 (32.1)

91 (67.9)

 

CEA, SCC-Ag

134

55 (41.0)

79 (59.0)

 

or CYFRA21-1

    

CEA, SCC-Ag,

134

86 (64.2)

48 (35.8)

<0.001*

CYFRA21-1 or CDC25B-Abs

  1. Abs: antibodies; CEA: carcinoembryonic antigen; SCC-Ag: squamous cell carcinoma antigen; CYFRA21-1: cytokeratin 19 fragment antigen 21-1.
  2. *compared with either CEA, SCC-Ag or CYFRA21-1. Cut-off values: 5.0 ng/ml for CEA; 1.5 ng/ml for SCC-Ag; 3.5 ng/ml for CYFRA21-1