Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis

Table 3 Histopathology of delayed-type hypersensitivity (DTH) reactions, specifically following dendritic cell vaccines*

Literature source	CD4⁺T cells	CD8⁺T cells	CD20⁺B cells	CD56⁺NK cells	Distribution
Nestle, *et al* . (1998)[21]	CD45R0⁺ & CD4⁺	NM	NM	NM	perivascular
Bedrosian, *et al* . (2003)[24]	Few	numerous	NM	NM	perivascular
de Vries, *et al* . (2005)[23]	50-70%	30-50%	None	NM	perivascular
Nakai, *et al* . (2006)[22]	Majority	< CD4⁺	NM	NM	perivascular
Nakai (2009)[25]	≥ CD8+⁺	≤ CD4⁺	NM	None	Perivascular

NM = not mentioned
*Where reported, all were evaluated based on punch biopsies. The biopsy method was not described by Nestle (1998) and Nikai (2006).

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