Figure 4

Perivascular T-and B-cell infiltrate. (a) Prominent infiltrate of inflammatory cells composed of lymphocytes and macrophages. (b) CD3⁺ T-cells (brown chromagen) cluster around blood vessel. (c) CD20⁺ B-cells (brown chromagen) group peripheral to the T-cell zone. Bar = 100 μm in a-c. (d) Double-staining for CD20⁺ B-cells (brown membranous stain) and CD8 (purple membranous stain). Counter-staining with hematoxylin marks nuclei blue. Note the group of B-cells located distant from blood vessel and next to the perivascular zone. The latter is composed of purple T-cells (we show the CD8⁺ population here) Bar = 50 μm.