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Table 1 Correlations between clinicopathological characteristics and RBM3 mRNA (Cohort I) levels and protein expression (Cohort II)

From: Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer

 

Cohort I

 

Cohort II

  

RBM3 score

low

high

 

0

1

2

 

n (% for columns)

120 (45.6)

143 (54.4)

p-value

74 (49.0)

50 (33.1)

27 (17.9)

p-value

Histological subtype

      

mucinuos

0 (0.0)

0 (0.0)

0.887

4 (5.4)

4 (8.0)

3 (11.1)

0.395

serous

111 (92.5)

133 (93.0)

 

42 (56.8)

31 (62.0)

16 (59.3)

 

endometroid

9 (7.5)

9 (6.3)

 

17 (23.0)

12 (24.0)

5 (18.5)

 

clear cell

0 (0.0)

0 (0.0)

 

6 (8.1)

1 (2.0)

2 (7.4)

 

Brenner

0 (0.0)

0 (0.0)

 

0 (0.0)

0 (0.0)

1 (3.7)

 

adenocarcinoma nos

0 (0.0)

1 (0.7)

 

5 (6.8)

2 (4.0)

0 (0.0)

 

Differentiation grade

       

high

3 (2.5)

14 (9.8)

0.079

2 (2.7)

2 (4.0)

3 (11.1)

0.084

intermediate

40 (33.3)

48 (33.6)

 

17 (23.0)

13 (26.0)

9 (33.3)

 

low

77 (64.2)

78 (54.5)

 

55 (74.3)

35 (70.0)

15 (55.6)

 

missing

0 (0.0)

3 (2.1)

 

0 (0.0)

0 (0.0)

0 (0.0)

 

Stage

       

I

9 (7.5)

15 (10.5)

0.070

14 (18.9)

7 (14.0)

5 (18.5)

0.760

II

3 (2.5)

15 (10.5)

 

5 (6.8)

9 (18.0)

3 (11.1)

 

III

101 (84.2)

104 (72.7)

 

40 (54.1)

26 (52.0)

8 (29.6)

 

IV

7 (5.8)

9 (6.3)

 

9 (12.2)

6 (12.0)

7 (25.9)

 

missing

0 (0.0)

0 (0.0)

 

6 (8.1)

2 (4.0)

4 (14.8)

 
  1. Correlations were calculated using Spearman correlation test unless other specified.
  2. Kruskal-Wallis test (two-sided).