Figure 4

Tracking of BrdU-labeled neural stem cells at passage six in the ischemic brain of rat having undergone cell therapy for four weeks. A: a representative coronal section of a transplanted rat demonstrated the localization of reddish-brown colored BrdU+ cells (left panel) to the cortex, hippocampus, striatum and brain parenchyma near the third ventricle, and of a sham-operated normal control rat without BrdU postivity (right panel) B: migration of BrdU+ cells along the corpus callosum. C and D: small clusters of BrdU+ cells displaying a glial morphology. Scale bar: 75 μm.